-Pathology manual microtome : requires the operator to manually perform the slicing process, including fixing the tissue on the slicing table, adjusting the slice thickness, and using a blade for cutting. This method requires a high level of skill and experience from the operator, but in some cases, such as the handling of certain special tissues, manual slicers may be more advantageous.

-Semi automatic paraffin microtome : The slicing process is carried out through a highly automated system. The operator only needs to set the parameters, and the machine will automatically complete the slicing, staining, and other steps. This method reduces the difficulty of operation, improves work efficiency, and is suitable for processing large-scale samples.

Due to the higher degree of automation of semi-automatic paraffin microtome , their efficiency is much higher than that of manual slicers when processing large amounts of samples. Manual slicers may be more flexible and precise when processing small amounts of samples or special tissues.

-Pathological manual microtome : suitable for processing small amounts of samples, special tissues, and experiments with high requirements for slice quality. Manual slicers may have advantages in some special situations, such as the processing of certain special tissues.

In summary, manual pathology slicers and semi-automatic paraffin slicers each have their own advantages and disadvantages, and it is crucial to choose the appropriate equipment based on actual needs and experimental conditions.